# BRAF V600E mutation

BRAF V600E mutation

- for detecting antigens in haematological neoplasms, usually in - blood samples, and for determining ploidy , i.e. the number of sets of  chromosomes in the nucleus of  a cell. Although tradi - tional flow cytometry is of  limited value for tissue analysis, new applications of  image cytometric DNA analysis allow detection of  aneuploidy in tissue sections of  gastrointestinal cancers. 

Figure 11.29
Sanger sequencing showing wild-type
BRAF
(a)
and
a
BRAF
V600E mutation
(b)
(courtesy of Dr M Rodriguez-Justo,
UCL-AD, Cancer Institute, London, UK).

BRAF V600E mutation

- for detecting antigens in haematological neoplasms, usually in - blood samples, and for determining ploidy , i.e. the number of sets of  chromosomes in the nucleus of  a cell. Although tradi - tional flow cytometry is of  limited value for tissue analysis, new applications of  image cytometric DNA analysis allow detection of  aneuploidy in tissue sections of  gastrointestinal cancers. 

Figure 11.29
Sanger sequencing showing wild-type
BRAF
(a)
and
a
BRAF
V600E mutation
(b)
(courtesy of Dr M Rodriguez-Justo,
UCL-AD, Cancer Institute, London, UK).

BRAF V600E mutation

- for detecting antigens in haematological neoplasms, usually in - blood samples, and for determining ploidy , i.e. the number of sets of  chromosomes in the nucleus of  a cell. Although tradi - tional flow cytometry is of  limited value for tissue analysis, new applications of  image cytometric DNA analysis allow detection of  aneuploidy in tissue sections of  gastrointestinal cancers. 

Figure 11.29
Sanger sequencing showing wild-type
BRAF
(a)
and
a
BRAF
V600E mutation
(b)
(courtesy of Dr M Rodriguez-Justo,
UCL-AD, Cancer Institute, London, UK).