# Dermis

Dermis

The dermis constitutes 95% of  the skin and is structurally divided into a superﬁcial papillary layer, which is composed of delicate collagen and elastin ﬁbres in ground substance, into which a capillary and lymphatic network ramiﬁes, and a deeper reticular layer, which is composed of  coarse branching collagen, layered parallel to the skin surface ( Figure 45.1 ). - The epidermis and dermis meet at the dermoepidermal junction in a three-dimensional wave-like arrangement in - which epidermal rete ridges project down, inter digitating with the upward-pointing, dermal papillae containing vascular and lymphatic plexi. m - The skin also contains specialised cells such as Langerhans cells, whose role is to engulf  antigens and present them to T cells. Merkel cells, and Meissner’s and Pacinian corpuscles have roles in mechanosensation. - Dermis

The dermis constitutes 95% of  the skin and is structurally divided into a superﬁcial papillary layer, which is composed of delicate collagen and elastin ﬁbres in ground substance, into which a capillary and lymphatic network ramiﬁes, and a deeper reticular layer, which is composed of  coarse branching collagen, layered parallel to the skin surface ( Figure 45.1 ). - The epidermis and dermis meet at the dermoepidermal junction in a three-dimensional wave-like arrangement in - which epidermal rete ridges project down, inter digitating with the upward-pointing, dermal papillae containing vascular and lymphatic plexi. m - The skin also contains specialised cells such as Langerhans cells, whose role is to engulf  antigens and present them to T cells. Merkel cells, and Meissner’s and Pacinian corpuscles have roles in mechanosensation. - Dermis

The dermis constitutes 95% of  the skin and is structurally divided into a superﬁcial papillary layer, which is composed of delicate collagen and elastin ﬁbres in ground substance, into which a capillary and lymphatic network ramiﬁes, and a deeper reticular layer, which is composed of  coarse branching collagen, layered parallel to the skin surface ( Figure 45.1 ). - The epidermis and dermis meet at the dermoepidermal junction in a three-dimensional wave-like arrangement in - which epidermal rete ridges project down, inter digitating with the upward-pointing, dermal papillae containing vascular and lymphatic plexi. m - The skin also contains specialised cells such as Langerhans cells, whose role is to engulf  antigens and present them to T cells. Merkel cells, and Meissner’s and Pacinian corpuscles have roles in mechanosensation. -