# Malignant lymphoma

Malignant lymphoma

In the past, many malignant lymphomas were diagnosed as small round-cell anaplastic carcinomas. Response to irradiation is dramatic ( Figure 55.27 ) and radical surgery is unnecessary Antoine Marfan , 1858–1942, paediatrician, University of  Paris, France. Bosselated: covered in multiple bosses (small protuberences). - once the diagnosis is established by biopsy . In patients with tracheal compression, isthmusectomy is the most appropriate - form of  biopsy , although the response to therapy is so rapid - that this should rarely be necessary unless there has been di ffi culty in making a histological diagnosis. The prognosis is good, particularly if  there is no involvement of  cervical lymph nodes. Rarely , the tumour is part of widespread malignant lymphoma disease and the prognosis in these cases is worse. Most lymphomas occur against a background of  lymphocytic thyroiditis. 

-
(b)
Figure 55.27
Magnetic resonance imaging scans of extensive
malignant lymphoma
(a)
before and
(b)
after 7 days of external beam
radiotherapy (courtesy of Dr FW Smith, Aberdeen, UK).

Malignant lymphoma

In the past, many malignant lymphomas were diagnosed as small round-cell anaplastic carcinomas. Response to irradiation is dramatic ( Figure 55.27 ) and radical surgery is unnecessary Antoine Marfan , 1858–1942, paediatrician, University of  Paris, France. Bosselated: covered in multiple bosses (small protuberences). - once the diagnosis is established by biopsy . In patients with tracheal compression, isthmusectomy is the most appropriate - form of  biopsy , although the response to therapy is so rapid - that this should rarely be necessary unless there has been di ffi culty in making a histological diagnosis. The prognosis is good, particularly if  there is no involvement of  cervical lymph nodes. Rarely , the tumour is part of widespread malignant lymphoma disease and the prognosis in these cases is worse. Most lymphomas occur against a background of  lymphocytic thyroiditis. 

-
(b)
Figure 55.27
Magnetic resonance imaging scans of extensive
malignant lymphoma
(a)
before and
(b)
after 7 days of external beam
radiotherapy (courtesy of Dr FW Smith, Aberdeen, UK).