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B. SSRIs © SPMM Course B. SSRIs  The SSRIs are rapidly absorbed. Sertraline availability may be ...

A. Tricyclic antidepressants: © SPMM Course 4. Clinically relevant kinetics and interactions: A. ...

4. Clinically relevant kinetics and interactions:

D. Changes with renal impairment: © SPMM Course may be 600ml/min as compared to 1200ml/min in you...

C. Changes in pregnancy:

B. Changes in neonates:

A. Changes in the elderly © SPMM Course 3. Variables affecting pharmacokinetics: A. Changes in th...

3. Variables affecting pharmacokinetics:

2. Indices of safety and efficacy: © SPMM Course 2. Indices of safety and efficacy: Quantal or do...

G. Elimination kinetics: © SPMM Course fall in the plasma drug concentration, which is caused by ...

F. Excretion: © SPMM Course F. Excretion: The major routes of drug excretion are via urine, faece...

E. Metabolism of drugs: © SPMM Course for lithium carbonate or Clozaril vs. zaponex for clozapine...

D. Bioavailability: © SPMM Course D. Bioavailability: Bioavailability refers to how much of an ad...

Blood-brain barrier © SPMM Course (Chadwick et al., 2005). Protein binding interactions become re...

C. Distribution: © SPMM Course C. Distribution: Distribution of a drug refers to ‘where’ in the b...

B. Permeation: © SPMM Course B. Permeation: Permeation of a drug is defined as the lipid membrane...

Intravenous routes © SPMM Course Size of drug particle Solubility of the drug Properties of inte...

Intramuscular administration

Oral administration © SPMM Course Principles of pharmacokinetics Pharmacokinetics refers to the ...

A. Absorption