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6.10 Neurodegenerative disorders in older people 601 ESSENTIALS Neurodegenerative disorders are a...

6.1 Ageing and clinical medicine 511 6.1 Ageing and clinical medicine Claire Steves and Neil Pend...

5.7 Medical management of breast cancer 505 ESSENTIALS Early breast cancer Most patients with bre...

5.6 Systemic treatment and radiotherapy 497 ESSENTIALS Cancer therapy is underpinned by a detaile...

5.5 Clinical features and management 487 ESSENTIALS Patients with cancer may present after detect...

5.4 Cancer immunity and immunotherapy 471 ESSENTIALS The development of a cancer in an immunologi...

5.3 The genetics of inherited cancers 456 ESSENTIALS All cancer can be termed ‘genetic’ as the di...

5.2 The nature and development of cancer: Cancer mutations and their implications 445 ESSENTIALS ...

5.1 Epidemiology of cancer 411

4.7 Principles of transplantation immunology 392 ESSENTIALS The survival of transplanted organs r...

4.6 Autoimmunity 379 ESSENTIALS Autoimmune diseases occur when a sustained, specific, adaptive im...

4.5 Allergy 368 ESSENTIALS Allergy is common and becoming commoner: it now affects about one-​thi...

4.4 Immunodeficiency 337 ESSENTIALS Immunodeficiency is caused by failure of a component of the i...

4.3 Adaptive immunity 325 ESSENTIALS Following the innate immune response, which acts very rapidl...

4.2 The complement system 315 ESSENTIALS The complement system, consisting of soluble and membran...

4.1 The innate immune system 307 ESSENTIALS The innate immune system comprises evolutionarily anc...

30.2 Practical procedures 6644 Elaine Jolly, Sian Coggle, and John D. Firth ESSENTIALS Key practi...

30.1 Acute medical presentations 6591 Sian Coggle, Elaine Jolly, and John D. Firth ESSENTIALS Thi...

3.9 Circulating DNA for molecular diagnostics 299 ESSENTIALS Short fragments of cell-​free DNA ar...

3.8 The evolution of therapeutic antibodies 296 ESSENTIALS The development of rodent monoclonal a...