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22.6.12 Acquired haemolytic anaemia 5479 Amy Power
22.6.12 Acquired haemolytic anaemia 5479 Amy Powers and Leslie Silberstein 22.6.12 Acquired haemolytic anaemia 5479 Uyoga S, et al. (2015). Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children on the coast of K...
22.6.2 Anaemia pathophysiology, classification, an
22.6.2 Anaemia: pathophysiology, classification, and clinical features 5359 David J. Weatherall† and Chris Hatton 22.6.2 Anaemia: pathophysiology, classification, and clinical features 5359 Basak A, et al. (2015). BCL11A deletions result in fetal hemoglobin p...
22.6.3 Anaemia as a challenge to world health 5366
22.6.3 Anaemia as a challenge to world health 5366 David J. Roberts and David J. Weatherall† section 22 Haematological disorders 5366 patient depends mainly on the severity of the anaemia and its cause. For example, a young patient with a haemoglobin level of...
22.6.4 Iron metabolism and its disorders 5371 Timo
22.6.4 Iron metabolism and its disorders 5371 Timothy M. Cox and John B. Porter 22.6.4 Iron metabolism and its disorders 5371 World Health Organization (1968). Nutritional anaemias. Technical Report Series No. 405. World Health Organization, Geneva. World Hea...
22.6.5 Anaemia of inflammation 5402 Sant- Rayn Pas
22.6.5 Anaemia of inflammation 5402 Sant- Rayn Pasricha and Hal Drakesmith section 22 Haematological disorders 5402 Taher AT, et al. (2012). Deferasirox reduces iron overload significantly in nontransfusion-dependent thalassemia: 1-year results from a pros...
22.6.6 Megaloblastic anaemia and miscellaneous def
22.6.6 Megaloblastic anaemia and miscellaneous deficiency anaemias 5407 A.V. Hoffbrand 22.6.6 Megaloblastic anaemia and miscellaneous deficiency anaemias 5407 these conditions may mobilize iron from macrophage stores, easing functional iron deficiency and fac...
22.6.7 Disorders of the synthesis or function of h
22.6.7 Disorders of the synthesis or function of haemoglobin 5426 Deborah Hay and David J. Weatherall† section 22 Haematological disorders 5426 Stabler SP (2013). Clinical practice. Vitamin B12 deficiency. N Eng J Med, 368, 149–60. Toh B-H, et al. (2012). Cu...
22.6.8 Anaemias resulting from defective maturatio
22.6.8 Anaemias resulting from defective maturation of red cells 5450 Stephen J. Fuller and James S. Wiley section 22 Haematological disorders 5450 Treatment In cases of chronic acquired methaemoglobinaemia, the drug or chemical agent should be removed where ...
22.6.9 Disorders of the red cell membrane 5456 Pat
22.6.9 Disorders of the red cell membrane 5456 Patrick G. Gallagher section 22 Haematological disorders 5456 Haas D, et al. (2007). New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes. Evidence from a core dataset of ...
22.7 Haemostasis 5490 22.7.1 The biology of haemos
22.7 Haemostasis 5490 22.7.1 The biology of haemostasis and thrombosis 5490 Gilbert C. White, II, Harold R. Roberts, and Nigel S. Key CONTENTS 22.7.1 The biology of haemostasis and thrombosis 5490 Gilbert C. White, II, Harold R. Roberts, and Nigel S. Key 22....
22.7.2 Evaluation of the patient with a bleeding t
22.7.2 Evaluation of the patient with a bleeding tendency 5509 Trevor Baglin 22.7.2 Evaluation of the patient with a bleeding tendency 5509 matrix. U-PA associates with the urokinase plasminogen-activator receptor (u-PAR). Antiplasmin Antiplasmin is the ph...
22.7.3 Thrombocytopenia and disorders of platelet
22.7.3 Thrombocytopenia and disorders of platelet function 5520 Nicola Curry and Susie Shapiro
22.7.4 Genetic disorders of coagulation 5532 Elean
22.7.4 Genetic disorders of coagulation 5532 Eleanor S. Pollak and Katherine A. High section 22 Haematological disorders 5532 Disorders of platelet procoagulant activity Scott syndrome is an extremely rare autosomal recessive condition. Reduced negatively cha...
22.7.5 Acquired coagulation disorders 5546 T.E. Wa
22.7.5 Acquired coagulation disorders 5546 T.E. Warkentin section 22 Haematological disorders 5546 Gene therapy in haemophilia High KA (2005). Gene transfer for hemophilia: can therapeutic ef- ficacy in large animals be safely translated to patients? J Thromb...
22.8.2 Haemopoietic stem cell transplantation 5579
22.8.2 Haemopoietic stem cell transplantation 5579 E.C. Gordon- Smith and Emma C. Morris 22.8.2 Haemopoietic stem cell transplantation 5579 22.8.2 Haemopoietic stem cell transplantation E.C. Gordon-Smith and Emma C. Morris ESSENTIALS Haemopoietic stem cells...
ESSENTIALS
ESSENTIALS section 22 Haematological disorders 5520 and often mild, as compared with thrombocytopenia associated with inadequate platelet production (mentioned previously). Rarely, an autoantibody to a specific clotting factor, such as factor VIII, produces a...
Transfusion and transplantation 5563 22.8.1 Blood
Transfusion and transplantation 5563 22.8.1 Blood transfusion 5563 D.S. Giovanniello and E.L. Snyder CONTENTS 22.8.1 Blood transfusion 5563 D.S. Giovanniello and E.L. Snyder 22.8.2 Haemopoietic stem cell transplantation 5579 E.C. Gordon-Smith and Emma C. ...
23.1 Structure and function of skin 5591 John A. M
23.1 Structure and function of skin 5591 John A. McGrath ESSENTIALS Skin provides a mechanical and immunological barrier against the external environment, but has further roles in thermoregulation, me- tabolism, and the regulation of fluid balance, as well as ...