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19 - PART 12 Endocrinology and Metabolism

01 - SECTION 1 Endocrinology

SECTION 1 Endocrinology Section 1 Endocrinology J. Larry Jameson Approach to the Patient with En...

02 - 388 Approach to the Patient with Endocrine Disorders

388 Approach to the Patient with Endocrine Disorders Section 1 Endocrinology J. Larry Jameson Ap...

03 - 389 Mechanisms of Hormone Action

389 Mechanisms of Hormone Action ultrasound, and thyroid scan are also used for the diagnosis of ...

04 - 390 Physiology of Anterior Pituitary Hormones

390 Physiology of Anterior Pituitary Hormones Positive feedback control also occurs but is not we...

05 - 391 Hypopituitarism

391 Hypopituitarism Shlomo Melmed, J. Larry Jameson Hypopituitarism Deficient production of anter...

06 - 392 Pituitary Tumor Syndromes

392 Pituitary Tumor Syndromes is associated with decreased libido and potency, infertility, decre...

07 - 393 Disorders of the Neurohypophysis

393 Disorders of the Neurohypophysis Diagnosis is based on demonstrating elevated serum free T4 l...

08 - 394 Thyroid Gland Physiology and Testing

394 Thyroid Gland Physiology and Testing as pseudohyponatremia (due to raised lipids or protein) ...

09 - 395 Hypothyroidism

395 Hypothyroidism hormone (“cold” nodules, see Chap. 397, Fig 397-3A), and these are more likely...

10 - 396 Hyperthyroidism and Other Causes of Thyrotoxicosis

396 Hyperthyroidism and Other Causes of Thyrotoxicosis be approximated by decreasing the upper li...

11 - 397 Thyroid Nodular Disease and Thyroid Cancer

397 Thyroid Nodular Disease and Thyroid Cancer suppression of the thyroid (Wolff-Chaikoff effect)...

12 - 398 Disorders of the Adrenal Cortex

398 Disorders of the Adrenal Cortex on a negative result. Assuming a 25–30% ROM for nodules with ...

13 - 399 Pheochromocytoma

399 Pheochromocytoma Fleseriu M et al: Consensus on diagnosis and management of Cushing’s disease...

14 - 400 Multiple Endocrine Neoplasia Syndromes

400 Multiple Endocrine Neoplasia Syndromes TABLE 399-3  Patterns of Occurrence in Inherited Pheoc...

15 - 401 Autoimmune Polyendocrine Syndromes

401 Autoimmune Polyendocrine Syndromes Peter A. Gottlieb, Aaron W. Michels Autoimmune Polyendocri...

16 - SECTION 2 Sex- and Gender-Based Medicine

SECTION 2 Sex- and Gender-Based Medicine Section 2 Sex- and Gender-Based Medicine Courtney Finla...

17 - 402 Sex Development

402 Sex Development Section 2 Sex- and Gender-Based Medicine Courtney Finlayson, J. Larry Jameso...

18 - 403 Disorders of the Testes and Male Reproductive System

403 Disorders of the Testes and Male Reproductive System increased risk for germ cell cancer, req...

19 - 404 Disorders of the Female Reproductive System

404 Disorders of the Female Reproductive System detecting AAS use. Illicit testosterone use is de...

20 - 405 Menstrual Disorders and Pelvic Pain

405 Menstrual Disorders and Pelvic Pain Approximately 50% of girls with congenital hypogonadotrop...

21 - 406 Hirsutism

406 Hirsutism as appropriate. Neuromuscular and psychosomatic etiologies should also be considere...

22 - 407 Menopause and Postmenopausal Hormone Therapy

407 Menopause and Postmenopausal Hormone Therapy JoAnn E. Manson, Shari S. Bassuk Menopause and P...

23 - 408 Infertility and Contraception

408 Infertility and Contraception family history of breast cancer in a first-degree relative or o...

24 - 409 Sexual Dysfunction

409 Sexual Dysfunction Kevin T. McVary Sexual Dysfunction Male sexual dysfunction affects up to 3...

25 - 410 Women’s Health

410 Women’s Health treatments due to health concerns or are unable to use them due to a history o...

26 - 411 Men’s Health

411 Men’s Health ■ ■SUBSTANCE ABUSE AND TOBACCO (See also Chaps. 464 and 465) Substance abuse is ...

28 - SECTION 3 Obesity, Diabetes Mellitus, and Metabolic Syndrome

SECTION 3 Obesity, Diabetes Mellitus, and Metabolic Syndrome Fenway Health: Glossary of LGBT term...

29 - 413 Pathobiology of Obesity

413 Pathobiology of Obesity Fenway Health: Glossary of LGBT terms for health care teams. February...

30 - 414 Evaluation and Management of Obesity

414 Evaluation and Management of Obesity FATTY LIVER DISEASE  Obesity is strongly associated with...

32 - 416 Diabetes Mellitus- Management and Therapies

416 Diabetes Mellitus: Management and Therapies Diabetes Mellitus: Management and Therapies Alvin...

33 - 417 Diabetes Mellitus- Complications

417 Diabetes Mellitus: Complications comorbidities and risk factors (e.g., hypertension, CVD), ne...

34 - 418 Hypoglycemia

418 Hypoglycemia Pneumonia, urinary tract infections, and skin and soft tissue infec­ tions are a...

35 - 419 Disorders of Lipoprotein Metabolism

419 Disorders of Lipoprotein Metabolism Acknowledgment The author acknowledges contributions of t...

36 - 420 The Metabolic Syndrome

420 The Metabolic Syndrome of choice in children and in women who are pregnant, lactating, or act...

37 - SECTION 4 Disorders of Bone and Mineral Metabolism

SECTION 4 Disorders of Bone and Mineral Metabolism Section 4 Disorders of Bone and Mineral Metab...

38 - 421 Bone and Mineral Metabolism in Health and Disease

421 Bone and Mineral Metabolism in Health and Disease Section 4 Disorders of Bone and Mineral Me...

39 - 422 Disorders of the Parathyroid Gland and Calcium Homeostasis

422 Disorders of the Parathyroid Gland and Calcium Homeostasis relatively inaccessible, since ost...

40 - 423 Osteoporosis

423 Osteoporosis supplementation is sometimes needed for weeks to a month or two until bone defec...

41 - 424 Paget’s Disease and Other Dysplasias of Bone

424 Paget’s Disease and Other Dysplasias of Bone Osteoporosis and related fractures are serious s...

42 - SECTION 5 Disorders of Intermediary Metabolism

SECTION 5 Disorders of Intermediary Metabolism by short bulbous roots, pulp calcification, and ra...

43 - 425 Heritable Disorders of Connective Tissue

425 Heritable Disorders of Connective Tissue by short bulbous roots, pulp calcification, and radi...

44 - 426 Hemochromatosis

426 Hemochromatosis TREATMENT Marfan and Loeys-Dietz Syndromes Patients should be advised that va...

45 - 427 Wilson’s Disease

427 Wilson’s Disease ■ ■ROLE OF HFE MUTATIONS IN OTHER LIVER DISEASES There is considerable inter...

46 - 428 The Porphyrias

428 The Porphyrias TREATMENT Wilson’s Disease COPPER CHELATION The era of successful treatment of...

47 - 429 Lysosomal Storage Diseases

429 Lysosomal Storage Diseases stimulates tanning, is administered subcutaneously every 2 months ...

49 - 431 Inherited Disorders of Amino Acid Metabolism in Adults

431 Inherited Disorders of Amino Acid Metabolism in Adults ethnic populations, but clinical sympt...

50 - 432 Inherited Defects of Membrane Transport

432 Inherited Defects of Membrane Transport Nicola Longo Inherited Defects of Membrane Transport ...