SECTION 3 Cell biology
3.1 The cell 209
3.1 The cell 209 ESSENTIALS The cell is a dynamic entity. Cells are not simply building blocks th...
3.2 The genomic basis of medicine 218
3.2 The genomic basis of medicine 218 ESSENTIALS It is now possible to determine the entire DNA i...
3.3 Cytokines 236
3.3 Cytokines 236 ESSENTIALS Cytokines are small glycoprotein mediators that are involved in ever...
3.4 Ion channels and disease 246
3.4 Ion channels and disease 246 ESSENTIALS Ion channels are membrane proteins that act as gated ...
3.5 Intracellular signalling 256
3.5 Intracellular signalling 256 ESSENTIALS This chapter outlines the general principles of intra...
3.6 Apoptosis in health and disease 266
3.6 Apoptosis in health and disease 266 ESSENTIALS Apoptosis is the process by which single cells...
3.7 Stem cells and regenerative medicine 281
3.7 Stem cells and regenerative medicine 281 ESSENTIALS There is a great and unmet need for treat...
3.8 The evolution of therapeutic antibodies 296
3.8 The evolution of therapeutic antibodies 296 ESSENTIALS The development of rodent monoclonal a...
3.9 Circulating DNA for molecular diagnostics 299
3.9 Circulating DNA for molecular diagnostics 299 ESSENTIALS Short fragments of cell-free DNA ar...