Fig. 21.10.1.1 Schematic of a glomerulus. In diabe

Fig. 21.10.1.1 Schematic of a glomerulus. In diabetes, there is relativeafferent arteriolar dilatation and angiotensin II- induced efferent arteriolarconstriction. This leads to increased glomerular capillary flow andpressure resulting in elevated GFR (hyperfiltration) and increased albuminfiltration. Blockade of the renin– angiotensin system dilates the efferentarteriole and reduces GFR and capillary pressure.