Fig. 21.10.2.1 Glomerular histology of ANCA- assoc

Fig. 21.10.2.1 Glomerular histology of ANCA- associated vasculitis. (a) A glomerulus showing focal necrosiswith an early crescentic reaction (arrow). (b) Glomerular macrophage infiltration (brown) illustrated by CD68staining. (c) Severe glomerular involvement with widespread necrosis, a circumferential crescent, and collapse ofthe glomerular tuft. (d) Massive periglomerular leucocyte infiltration occurring around an affected glomerulus.