07 - Chapter 2 Bipolar disorder
01 - Lithium
Lithium
02 - Mechanism of action
Mechanism of action
03 - Clinical indications
Clinical indications The Maudsley® Prescribing Guidelines in Psychiatry, Fifteenth Edition. David...
04 - Lithium and suicide
Lithium and suicide
05 - Plasma levels
Plasma levels Bipolar disorder CHAPTER 2 Prophylaxis of unipolar depression Lithium is significan...
06 - Formulations
Formulations
07 - Adverse effects
Adverse effects
08 - Lithium toxicity
Lithium toxicity 282 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 Formulations Th...
09 - Pre treatment tests
Pre-treatment tests
10 - On treatment monitoring12,58
On-treatment monitoring12,58
11 - Discontinuation
Discontinuation Bipolar disorder CHAPTER 2 Above 2mmol/L, increased disorientation and seizures u...
12 - Interactions with other drugs7072
Interactions with other drugs70–72 284 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER...
13 - References
References 286 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 fenbufen, fenoprofen,...
14 - Valproate
Valproate
15 - Mechanism of action1
Mechanism of action1
16 - Formulations
Formulations
17 - Indications
Indications Bipolar disorder CHAPTER 2 Valproate Mechanism of action1 Valproate is a simple branc...
18 - Plasma levels
Plasma levels 290 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 less effective but...
19 - Adverse effects
Adverse effects
20 - Pre treatment tests
Pre-treatment tests
21 - On treatment monitoring
On-treatment monitoring
22 - Discontinuation
Discontinuation Bipolar disorder CHAPTER 2 Adverse effects Valproate can cause both gastric irrit...
23 - Use in women of child bearing age
Use in women of child-bearing age
24 - Interactions with other drugs
Interactions with other drugs 292 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 Us...
25 - References
References Bipolar disorder CHAPTER 2 References Rosenberg G. The mechanisms of action of valpro...
26 - Carbamazepine
Carbamazepine
27 - Mechanism of action1
Mechanism of action1
28 - Formulations
Formulations
29 - Indications
Indications Bipolar disorder CHAPTER 2 Carbamazepine Mechanism of action1 Carbamazepine blocks vo...
30 - Plasma levels
Plasma levels
31 - Adverse effects1
Adverse effects1 296 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 considered to b...
32 - Pre treatment tests
Pre-treatment tests
33 - On treatment monitoring
On-treatment monitoring
34 - Discontinuation
Discontinuation
35 - Use in women of child bearing age
Use in women of child-bearing age
36 - Interactions with other drugs4144
Interactions with other drugs41–44 Bipolar disorder CHAPTER 2 and a specificity approaching 100% ...
37 - References
References 298 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 resulting in treatmen...
38 - Antipsychotic drugs in bipolar disorder
Antipsychotic drugs in bipolar disorder
39 - First generation antipsychotics
First-generation antipsychotics
40 - Second generation antipsychotics
Second-generation antipsychotics 300 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2...
41 - Specific antipsychotics
Specific antipsychotics Bipolar disorder CHAPTER 2 Bipolar depression In acute treatment of bipol...
42 - References
References Bipolar disorder CHAPTER 2 References ECNP. Neuroscience-based nomenclature (NbN). 2...
43 - Antipsychotic long acting injections in bipol
Antipsychotic long-acting injections in bipolar disorder Bipolar disorder CHAPTER 2 Antipsychotic...
44 - Conclusion
Conclusion 306 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 neither decreases nor...
45 - References
References Bipolar disorder CHAPTER 2 References Keramatian K, et al. Long-acting injectable se...
46 - Physical monitoring for people with bipolar d
Physical monitoring for people with bipolar disorder1,2 Physical monitoring for people with bipol...
47 - References
References Prolactin Children and adolescents only At start and if symptoms of raised prolactin d...
48 - Treatment of acute mania or hypomania
Treatment of acute mania or hypomania 310 The Maudsley® Prescribing Guidelines in Psychiatry CHAP...
49 - References
References 312 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 References Cipriani ...
50 - Rapid cycling bipolar affective disorder
Rapid-cycling bipolar affective disorder 316 The Maudsley® Prescribing Guidelines in Psychiatry C...
51 - References
References Bipolar disorder CHAPTER 2 References Miola A, et al. Prevalence and outcomes of rapi...
52 - Bipolar depression
Bipolar depression
53 - Meta analysis in bipolar depression
Meta-analysis in bipolar depression Bipolar disorder CHAPTER 2 Bipolar depression Bipolar depress...
54 - Summary of drug choice
Summary of drug choice
55 - References
References 322 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 Summary of drug choic...
56 - Prophylaxis in bipolar disorder
Prophylaxis in bipolar disorder 326 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 ...
57 - Optimising lithium treatment45
Optimising lithium treatment45
58 - Combination treatment
Combination treatment Bipolar disorder CHAPTER 2 risperidone LAI is well supported by RCTs39 and ...
59 - References
References Bipolar disorder CHAPTER 2 References Malhi GS, et al. The 2020 Royal Australian and ...
60 - Stopping lithium and mood stabilisers
Stopping lithium and mood stabilisers
61 - Rationale for stopping
Rationale for stopping
62 - Withdrawal effects from lithium and other moo
Withdrawal effects from lithium and other mood stabilisers Bipolar disorder CHAPTER 2 Stopping li...
63 - Evidence for long term treatment
Evidence for long-term treatment
64 - Duration of tapering
Duration of tapering
65 - Pattern of tapering
Pattern of tapering 332 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 2 Evidence for...
66 - Practice guide to tapering
Practice guide to tapering
67 - References
References Bipolar disorder CHAPTER 2 Practice guide to tapering ■ ■Patients should be told that ...