Skip to main content

273 - References

References

274 The Maudsley® Prescribing Guidelines in Psychiatry CHAPTER 1 ■ ■The likelihood of relapse or deterioration of the psychotic illness must be considered before discontinuing clozapine. ■ ■Consideration should be given to the possibility that, if the patient’s mental state deteriorates, they may retract their consent for chemotherapy. ■ ■When clozapine treatment is continued during chemotherapy, a collaborative approach is strongly recommended, involving an oncologist, a psychiatrist, a haematologist, a pharmacist, the patient and their relatives/carers and the relevant clozapine monitoring service. References

  1. Chrétien B, et  al. Haematologic malignancies associated with clozapine v. all other antipsychotic agents: a pharmacovigilance study in VigiBase(®). Psychol Med 2021; 51:1459–1466.
  2. Tiihonen J, et al. Long-­term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-­control and cohort study in Finland. Lancet Psychiatry 2022; 9:353–362.
  3. Cunningham NT, et  al. Continuation of clozapine during chemotherapy: a case report and review of literature. Psychosomatics 2014; 55:673–679.
  4. Bareggi C, et al. Clozapine and full-­dose concomitant chemoradiation therapy in a schizophrenic patient with nasopharyngeal cancer. Tumori 2002; 88:59–60.
  5. Hundertmark J, et al. Reintroduction of clozapine after diagnosis of lymphoma. Br J Psychiatry 2001; 178:576.
  6. Rosenstock J. Clozapine therapy during cancer treatment. Am J Psychiatry 2004; 161:175.
  7. Lee SY, et al. Combined antitumor chemotherapy in a refractory schizophrenic receiving clozapine. J Korean Neuropsychiatr Assoc 2000; 39:234–239.
  8. Usta NG, et al. Clozapine treatment of refractory schizophrenia during essential chemotherapy: a case study and mini review of a clinical dilemma. Ther Adv Psychopharmacol 2014; 4:276–281.
  9. Rosenberg I, et al. Restarting clozapine treatment during ablation chemotherapy and stem cell transplant for Hodgkin’s lymphoma. Am J Psychiatry 2007; 164:1438–1439.
  10. Goulet K, et al. Case report: clozapine given in the context of chemotherapy for lung cancer. Psychooncology 2008; 17:512–516.
  11. Frieri T, et al. Maintaining clozapine treatment during chemotherapy for non-­Hodgkin’s lymphoma. Prog Neuropsychopharmacol Biol Psychiatry 2008; 32:1611–1612.
  12. Sankaranarayanan A, et  al. Clozapine, cancer chemotherapy and neutropenia: dilemmas in management. Psychiatr Danub 2013; 25:419–422.
  13. De Berardis D, et al. Safety and efficacy of combined clozapine-­azathioprine treatment in a case of resistant schizophrenia associated with Behcet’s disease: a 2-­year follow-­up. Gen Hosp Psychiatry 2013; 35:213–211.
  14. Deodhar JK, et al. Clozapine and cancer treatment: adding to the experience and evidence. Indian J Psychiatry 2014; 56:191–193.
  15. Monga V, et al. Clozapine and concomitant chemotherapy in a patient with schizophrenia and new onset esophageal cancer. Psychooncology 2015; 24:971–972.
  16. Overbeeke MR, et al. Successful clozapine continuation during chemotherapy for the treatment of malignancy: a case report. Int J Clin Pharm 2016; 38:199–202.
  17. Campbell G, et al. Clozapine and chemotherapy: a dangerous couple or a necessary partnership? Drug Ther Bull 2022; 60:29–31.
  18. Wright T, et al. Should clozapine be discontinued in a patient receiving chemotherapy? Current Psychiatry 2022; 21:44–49.
  19. Whiskey E, et al. Restarting clozapine after neutropenia: evaluating the possibilities and practicalities. CNS Drugs 2007; 21:25–35.
  20. Silva E, et al. Clozapine rechallenge and initiation despite neutropenia-­ a practical, step-­by-­step guide. BMC Psychiatry 2020; 20:279.
  21. Kolli V, et  al. Treating chemotherapy induced agranulocytosis with granulocyte colony-­stimulating factors in a patient on clozapine. Psychooncology 2013; 22:1674–1675.