45 Skin and subcutaneous tissue

Acquired Campbell de Morgan spots These are arteriovenous fistulae at the dermal capillary level i...

Anomalies of skin metabolism Skin has the potential for a blood supply 20–100 times greater than ...

Atypical (dysplastic) naevus To be ‘atypical naevi’, lesions must have three of the following in ...

Basal cell carcinoma This is usually a slow-growing, locally invasive, malignant tumour of pluri...

Blood supply of the skin The body can be envisaged as three-dimensional segments of tissue calle...

Common vascular birthmarks Salmon patch A salmon patch is a vascular malformation that presents a...

Congenital/genetic disorders Neurofibromatosis There are two distinct neurofibromatosis (NF) syndro...

Cutaneous manifestations of generalised disease Many diseases have cutaneous manifestations that ...

Cutaneous squamous cell carcinoma SCC is a malignant tumour of keratinising cells of the epider...

Cylindroma (turban tumour) A variant of eccrine spiradenoma that coalesce when multiple on the s...

Dermis The dermis constitutes 95% of the skin and is structurally divided into a superficial papi...

Eccrine poroma (papillary syringoma) These are single raised or pedicled lesions found most often...

Epidermis The epidermis constitutes 5% of the skin and is composed of five layers of keratinised...

FUNCTION OF THE SKIN Skin and subcutaneous tissue have several important functions: /uni25CF Barr...

FUNCTIONAL ANATOMY AND PHYSIOLOGY OF SKIN Skin can be divided into two layers: the outer epidermi...

FURTHER READING Calonje JE, Brenn T , Lazar A, Billings S. McKee’s pathology of the skin , 5th ed...

Giant congenital pigmented naevus or giant hairy naevus This hamartoma of naevo-melanocytes cause...

Giant congenital pigmented naevus or giant hairy naevus This hamartoma of naevo-melanocytes cause...

Hair follicles Trichoepithelioma These are small skin-coloured nodules found most often in the na...

Infections Skin and soft-tissue infections can be localised or spreading, necrotising or non-necr...

Introduction No content extracted automatically.

Learning objectives To understand: The structure and functional properties of skin • The classi /...

Necrotising fasciitis Meleney’s synergistic gangrene and Fournier’s gangrene are variants of a s...

PATHOPHYSIOLOGY OF THE SKIN AND SUBCUTANEOUS TISSUES Radiation damage UVR and ionising radiation ...

PATHOPHYSIOLOGY OF THE SKIN AND SUBCUTANEOUS TISSUES Radiation damage UVR and ionising radiation ...

Pilomatrixoma (calcifying epithelioma of Malherbe) These are benign hair matrix cell tumours that...

Premalignant lesions Extramammary Paget’s disease (intraepidermal adenocarcinoma) This occurs in ...

Premalignant lesions Extramammary Paget’s disease (intraepidermal adenocarcinoma) This occurs in ...

Premalignant lesions Extramammary Paget’s disease (intraepidermal adenocarcinoma) This occurs in ...

Purpura fulminans This is a relatively rare condition in which intravascular throm - bosis produc...

SKIN TUMOURS Benign lesions Basal cell papilloma (seborrhoeic keratosis, senile keratosis, verruc...

Skin adnexa Adnexal structures such as hair follicles, sebaceous glands and sweat glands span bo...

Skin and soft-tissue cysts Milia Small, hard, keratin retention cysts ( Figure 45.11 ) seen both ...

Skin dimensions The skin is a large organ. In an adult it may have an area of 2 1–2 /uni00A0 m an...

Sweat glands Cystadenoma (hydrocystadenomas, hidradenomas) These are 1- to 3-cm translucent blue ...

VASCULAR LESIONS Congenital: haemangiomata and vascular malformations These can be subclassified b...

VASCULAR LESIONS Congenital: haemangiomata and vascular malformations These can be subclassified b...

WEBSITE ADDRESSES American Joint Committee on Cancer for TNM classifications of tumours and up-to-...

WOUNDS Congenital Cutis aplasia congenita This is a rare condition characterised by the congenita...