Anomalies of skin metabolism

Anomalies of skin metabolism

Skin has the potential for a blood supply 20–100 times greater than its metabolic and thermoregulatory requirements. This apparent excess enables restitution of mechanical integrity after the myriad of trivial injuries (scratching, stretching, compressing, thermal) to which skin is subjected; however, blood supply is inadequate to support full-thickness wound healing, which requires primary closure or granulation tissue. Skin functions optimally at temperatures below body core temperature and can tolerate long periods of ischaemia, allow ing it to be both grafted and/or expanded for use in recon struction. Anomalies of skin metabolism

Skin has the potential for a blood supply 20–100 times greater than its metabolic and thermoregulatory requirements. This apparent excess enables restitution of mechanical integrity after the myriad of trivial injuries (scratching, stretching, compressing, thermal) to which skin is subjected; however, blood supply is inadequate to support full-thickness wound healing, which requires primary closure or granulation tissue. Skin functions optimally at temperatures below body core temperature and can tolerate long periods of ischaemia, allow ing it to be both grafted and/or expanded for use in recon struction. Anomalies of skin metabolism

Skin has the potential for a blood supply 20–100 times greater than its metabolic and thermoregulatory requirements. This apparent excess enables restitution of mechanical integrity after the myriad of trivial injuries (scratching, stretching, compressing, thermal) to which skin is subjected; however, blood supply is inadequate to support full-thickness wound healing, which requires primary closure or granulation tissue. Skin functions optimally at temperatures below body core temperature and can tolerate long periods of ischaemia, allow ing it to be both grafted and/or expanded for use in recon struction.