Malignant lymphoma

Malignant lymphoma

In the past, many malignant lymphomas were diagnosed as small round-cell anaplastic carcinomas. Response to irradiation is dramatic ( Figure 55.27 ) and radical surgery is unnecessary Antoine Marfan , 1858–1942, paediatrician, University of Paris, France. Bosselated: covered in multiple bosses (small protuberences). - once the diagnosis is established by biopsy . In patients with tracheal compression, isthmusectomy is the most appropriate - form of biopsy , although the response to therapy is so rapid - that this should rarely be necessary unless there has been di ffi culty in making a histological diagnosis. The prognosis is good, particularly if there is no involvement of cervical lymph nodes. Rarely , the tumour is part of widespread malignant lymphoma disease and the prognosis in these cases is worse. Most lymphomas occur against a background of lymphocytic thyroiditis.

(b) Figure 55.27 Magnetic resonance imaging scans of extensive malignant lymphoma (a) before and (b) after 7 days of external beam radiotherapy (courtesy of Dr FW Smith, Aberdeen, UK).

Malignant lymphoma

In the past, many malignant lymphomas were diagnosed as small round-cell anaplastic carcinomas. Response to irradiation is dramatic ( Figure 55.27 ) and radical surgery is unnecessary Antoine Marfan , 1858–1942, paediatrician, University of Paris, France. Bosselated: covered in multiple bosses (small protuberences). - once the diagnosis is established by biopsy . In patients with tracheal compression, isthmusectomy is the most appropriate - form of biopsy , although the response to therapy is so rapid - that this should rarely be necessary unless there has been di ffi culty in making a histological diagnosis. The prognosis is good, particularly if there is no involvement of cervical lymph nodes. Rarely , the tumour is part of widespread malignant lymphoma disease and the prognosis in these cases is worse. Most lymphomas occur against a background of lymphocytic thyroiditis.

(b) Figure 55.27 Magnetic resonance imaging scans of extensive malignant lymphoma (a) before and (b) after 7 days of external beam radiotherapy (courtesy of Dr FW Smith, Aberdeen, UK).