Microscopic features of inflammation

Microscopic features of inflammation

Acute inflammation is characterised histologically by neutro - phils (polymorphonuclear leukocytes), erosion or ulceration ( Figure 11.18 ) and chronic inflammation by lymphocytes and plasma cells. Other inflammatory cells include eosino - phils ( Figure 11.19 ) , mast cells and histiocytes. Granulomas (collections of epithelioid histiocytes) ( Figure 11.20a ) raise the possibility of mycobacterial infection ( Figure 11.20b ), fungal ’s disease or a reaction infection, parasites, sarcoidosis, Crohn to foreign material, among numerous other possible causes. s may reflect parasitic infection or Eosinophils in large number allergy . Interpretation depends heavily on the site and clinical setting.

Figure 11.18 An acute in /f_l ammatory process characterised by numer ous neutrophils. Note the typical multilobated nuclei (arrows). Figure 11.19 Oesophageal mucosa in /f_i ltrated by numerous eosino phils with bright red cytoplasm, many of which are forming clusters. Eosinophils may re /f_l ect allergy, parasitic infection or a wide variety of other causes. In this example, the clinicopathological diagnosis was eosinophilic oesophagitis.

Microscopic features of inflammation

Acute inflammation is characterised histologically by neutro - phils (polymorphonuclear leukocytes), erosion or ulceration ( Figure 11.18 ) and chronic inflammation by lymphocytes and plasma cells. Other inflammatory cells include eosino - phils ( Figure 11.19 ) , mast cells and histiocytes. Granulomas (collections of epithelioid histiocytes) ( Figure 11.20a ) raise the possibility of mycobacterial infection ( Figure 11.20b ), fungal ’s disease or a reaction infection, parasites, sarcoidosis, Crohn to foreign material, among numerous other possible causes. s may reflect parasitic infection or Eosinophils in large number allergy . Interpretation depends heavily on the site and clinical setting.

Figure 11.18 An acute in /f_l ammatory process characterised by numer ous neutrophils. Note the typical multilobated nuclei (arrows). Figure 11.19 Oesophageal mucosa in /f_i ltrated by numerous eosino phils with bright red cytoplasm, many of which are forming clusters. Eosinophils may re /f_l ect allergy, parasitic infection or a wide variety of other causes. In this example, the clinicopathological diagnosis was eosinophilic oesophagitis.

Microscopic features of inflammation

Acute inflammation is characterised histologically by neutro - phils (polymorphonuclear leukocytes), erosion or ulceration ( Figure 11.18 ) and chronic inflammation by lymphocytes and plasma cells. Other inflammatory cells include eosino - phils ( Figure 11.19 ) , mast cells and histiocytes. Granulomas (collections of epithelioid histiocytes) ( Figure 11.20a ) raise the possibility of mycobacterial infection ( Figure 11.20b ), fungal ’s disease or a reaction infection, parasites, sarcoidosis, Crohn to foreign material, among numerous other possible causes. s may reflect parasitic infection or Eosinophils in large number allergy . Interpretation depends heavily on the site and clinical setting.

Figure 11.18 An acute in /f_l ammatory process characterised by numer ous neutrophils. Note the typical multilobated nuclei (arrows). Figure 11.19 Oesophageal mucosa in /f_i ltrated by numerous eosino phils with bright red cytoplasm, many of which are forming clusters. Eosinophils may re /f_l ect allergy, parasitic infection or a wide variety of other causes. In this example, the clinicopathological diagnosis was eosinophilic oesophagitis.