Hypothermic machine perfusion

Hypothermic machine perfusion

The transplant organ is placed in a sterile chamber and cold preservation fluid is continually recirculated through the vasculature at low temperature and pressure (30 /uni00A0 mmHg) ( Figure 88.4 ). The perfusion fluid is based on UW solution and some systems include oxygenation. This technique flushes the microcirculation more e ff ectively . There are trial and meta-analysis data showing that hypothermic machine perfu - sion reduces the rate of delayed graft function (DGF) in renal transplantation, but the e ff ect size is small.

® ® Figure 88.4 The LifePort hypothermic perfusion machine (LifePort Kidney Transporter courtesy of Organ Recovery Systems).