BRAF V600E mutation

BRAF V600E mutation

• for detecting antigens in haematological neoplasms, usually in - blood samples, and for determining ploidy , i.e. the number of sets of chromosomes in the nucleus of a cell. Although tradi - tional flow cytometry is of limited value for tissue analysis, new applications of image cytometric DNA analysis allow detection of aneuploidy in tissue sections of gastrointestinal cancers.

Figure 11.29 Sanger sequencing showing wild-type BRAF (a) and a BRAF V600E mutation (b) (courtesy of Dr M Rodriguez-Justo, UCL-AD, Cancer Institute, London, UK).

BRAF V600E mutation

• for detecting antigens in haematological neoplasms, usually in - blood samples, and for determining ploidy , i.e. the number of sets of chromosomes in the nucleus of a cell. Although tradi - tional flow cytometry is of limited value for tissue analysis, new applications of image cytometric DNA analysis allow detection of aneuploidy in tissue sections of gastrointestinal cancers.

Figure 11.29 Sanger sequencing showing wild-type BRAF (a) and a BRAF V600E mutation (b) (courtesy of Dr M Rodriguez-Justo, UCL-AD, Cancer Institute, London, UK).

BRAF V600E mutation

• for detecting antigens in haematological neoplasms, usually in - blood samples, and for determining ploidy , i.e. the number of sets of chromosomes in the nucleus of a cell. Although tradi - tional flow cytometry is of limited value for tissue analysis, new applications of image cytometric DNA analysis allow detection of aneuploidy in tissue sections of gastrointestinal cancers.

Figure 11.29 Sanger sequencing showing wild-type BRAF (a) and a BRAF V600E mutation (b) (courtesy of Dr M Rodriguez-Justo, UCL-AD, Cancer Institute, London, UK).