KIDNEY TRANSPLANTATION End-stage renal disease

KIDNEY TRANSPLANTATION End-stage renal disease

The incidence of end-stage renal disease (ESRD) in the UK is approximately 120 per million population and around 8000 people require renal replacement therapy annually . The lead ing causes of ESRD are diabetes, hypertension and chronic glomerulonephritis ( Summary box 88.1 ). ESRD is largely a disease of older adults with the mean age at commencement of renal replacement therapy being 64 years. Harvey Williams Cushing , 1869–1939, Professor of Surgery , Harvard University Medical School, Boston, MA, USA. Christian Johann Doppler , 1803–1853, Professor of Experimental Physics, Vienna, Austria, enunciated the Doppler principle in 1842. Common causes of ESRD /uni25CF /uni25CF /uni25CF /uni25CF /uni25CF /uni25CF /uni25CF

Chronic glomerulonephritis Polycystic kidney disease Diabetic nephropathy Chronic pyelonephritis Hypertension Obstructive uropathy Renal vascular disease