EPIDEMIOLOGY

EPIDEMIOLOGY

The incidence of congenital craniofacial anomalies varies in di ff erent parts of the world and is often not easy to quantify . Table 50.2 outlines the various incidences of the more common craniofacial abnormalities.

TABLE 50.2 Approximate incidence data from multiple sources. Condition Incidence Apert syndrome 1 in 100 /uni00A0 000 Pfeiffer syndrome 1 in 100 /uni00A0 000 Crouzon syndrome 1 in 62 /uni00A0 500 Treacher Collins syndrome 1 in 50 /uni00A0 000 Unicoronal synostosis 1 in 10 /uni00A0 000 Metopic synostosis 1 in 7000 Sagittal synostosis 1 in 5000 Hemifacial microsomia 1 in 3500 Neuro /f_i bromatosis 1 in 2600 Cleft lip and palate 1 in 600