Tumour thickness and depth of invasion

Tumour thickness and depth of invasion

Tumour thickness is measured as the maximum vertical dimension between the tumour surface and the deepest point of invasion. Although frequently used interchangeably with DOI, it is the latter that carries greater importance from a prognostic viewpoint as well as the propensity for metastases. DOI is the distance from the level of the basement membrane of the closest adjacent normal mucosa to the deepest point of the tumour invasion. Tumour thickness and depth of invasion

Tumour thickness is measured as the maximum vertical dimension between the tumour surface and the deepest point of invasion. Although frequently used interchangeably with DOI, it is the latter that carries greater importance from a prognostic viewpoint as well as the propensity for metastases. DOI is the distance from the level of the basement membrane of the closest adjacent normal mucosa to the deepest point of the tumour invasion.