Follicular carcinoma

Follicular carcinoma

Follicular carcinoma can normally only be di ff erentiated from follicular adenoma by the architecture on histology . For this reason, follicular lesions on FNA are unable to be diagnosed as malignant in the absence of clinical features such as metastases - ( Figure 55.24 ). Multiple foci of follicular carcinoma are seldom seen and lymph node involvement is much less common than in PTC. Blood-borne metastases are more common and the - eventual mortality rate, although still low , is twice that of PTC ( Figure 55.25 ). Hürthle cell tumours are a rare variant of follicular neo - plasm in which oxyphil (Hürthle, Askanazy) cells predominate histologically . Hürthle cell cancers are associated with a poor prognosis. - Follicular carcinoma

Follicular carcinoma can normally only be di ff erentiated from follicular adenoma by the architecture on histology . For this reason, follicular lesions on FNA are unable to be diagnosed as malignant in the absence of clinical features such as metastases - ( Figure 55.24 ). Multiple foci of follicular carcinoma are seldom seen and lymph node involvement is much less common than in PTC. Blood-borne metastases are more common and the - eventual mortality rate, although still low , is twice that of PTC ( Figure 55.25 ). Hürthle cell tumours are a rare variant of follicular neo - plasm in which oxyphil (Hürthle, Askanazy) cells predominate histologically . Hürthle cell cancers are associated with a poor prognosis. -