Differential diagnosis

Differential diagnosis

This includes all causes of cholestatic jaundice in a neonate; namely , α -antitrypsin deficiency , cholestasis associated with 1 intravenous feeding, choledochal cyst and inspissated bile syndrome. The most common di ff erential diagnoses are Alagille syndrome (biliary atresia, congenital heart disease, skeletal and other abnormalities), progressive familial intra- hepatic cholestasis and cystic fibrosis. Neonatal hepatitis is the most di ffi cult to di ff erentiate. Liver biopsy and radionuclide excretion scans are helpful.